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The effects on urine composition and pH of a single evening dose of alkaline potassium sodium citrate were studied in healthy subjects and recurrent calcium oxalate stone formers. This treatment resulted in a prompt and ificantly increased urinary pH with a duration until 10 a. In a retrospective study alkaline citrate was given in a single evening dose of 3.
The mean plus or minus standard deviation for duration of treatment was 3. ificantly reduced stone formation was recorded only in those on the evening dose regimen, which was associated with ificant improvement of urine composition. Because of favorable biochemical and clinical effects as well as good patient compliance with a single evening dose of alkaline citrate, this regimen appears to be an attractive alternative for long-term prevention of recurrent calcium stone formation.
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Save Cancel. Create a file for external citation management software Create file Cancel. of items displayed: 5 10 15 20 50 Create RSS Cancel. RSS Link Copy. Cite Display options Display options. Abstract The effects on urine composition and pH of a single evening dose of alkaline potassium sodium citrate were studied in healthy subjects and recurrent calcium oxalate stone formers. Similar articles Effects of citrate on the different phases of calcium oxalate crystallization.
Tiselius HG, et al. Scanning Microsc. PMID: Review. Effects of different doses of alkaline citrate on urine composition and crystallization of calcium oxalate. Berg C, et al. Urol Res. PMID: Alkaline citrate in prevention of recurrent calcium oxalate stones. Berg C. Scand J Urol Nephrol Suppl. Is calcium oxalate nucleation in postprandial urine of males with idiopathic recurrent calcium urolithiasis related to calcium phosphate nucleation and the intensity of stone formation?
Studies allowing insight into a possible role of urinary free citrate and protein. Schwille PO, et al. Clin Chem Lab Med. Dietary treatment of urinary risk factors for renal stone formation. Prezioso D, et al. Arch Ital Urol Androl. See all similar articles. Lindberg JS, et al. Ochsner J. Does citrate prevent nephrocalcinosis in preterm neonates?
Schell-Feith EA, et al. Pediatr Nephrol. Epub Oct Preventive treatment of nephrolithiasis with alkali citrate--a critical review. Mattle D, Hess B. Mattle D, et al. Epub May 4. A status report]. Rinnab L, et al. Urologe A. Risk formulas in calcium oxalate urolithiasis. Tiselius HG. World J Urol. See all "Cited by" articles. Publication types Research Support, Non-U. Gov't Actions. MeSH terms Adult Actions. Citric Acid Actions. Drug Administration Schedule Actions. Female Actions. Follow-Up Studies Actions. Humans Actions.
Hydrogen-Ion Concentration Actions. Male Actions. Middle Aged Actions. Retrospective Studies Actions. Time Factors Actions. Substances Calcium Phosphates Actions. Citrates Actions. Calcium Oxalate Actions. Calcium Actions. Copy Download.Single for the evening
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